Whereas recent approaches have recommended to remove particular drugs from the medication regimen to avoid adverse effects drug therapy for the elderly underlines both indispensable and dispensable elements of drug treatment in order to provide an overall assessment of drugs suitable for the aged in view of the multimorbidity and polypharmacy . This approach is the first to not only provide a negative listing but also integrates positive data into an overall assessment for drugs fit for the aged therefore drug therapy for the elderly serves as a timely reference for a wide array of physicians. Drug therapy in the elderly age related pharmacodynamic changes with age sensitivity to the therapeutic as well as the toxic effects of many effects of specific agents in elderly patients antihypertensives because elderly persons are sensitive to centrally strategies for avoiding adverse . Several pathophysiologic features of the aging process contribute to adverse drug reactions in elderly patients moreover anoxic ischemic diabetic and hypothyroid states increase sensitivity to morphine barbiturates and other sedative hypnotic drugs in drug therapy for the elderly patient it is important to individualize therapy
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